Dermatological
Non-surgical
Surgical
Expert care for a wide range of skin conditions, ensuring healthy, radiant skin.
Lesions & Bumps
Comprehensive care for skin lesions and bumps, promoting clear and healthy skin.
Lifting & Tightening
Advanced treatments to lift and lighten the skin, enhancing firmness and brightness.
Rejuvenation
Revitalize your skin with advanced treatments designed to restore a youthful glow.
Skin Treatments
Effective solutions for a variety of skin concerns, promoting clear and healthy skin.
Wellness
Holistic skincare approaches to support overall skin health and well-being.
Advanced, non-invasive treatments to rejuvenate your appearance without surgery.
Body Treatments
Transformative, non-invasive treatments to sculpt and tone your body effortlessly.
Facial Treatments
Rejuvenating facial treatments to refresh and enhance your natural radiance.
Hair Treatments
Advanced treatments to restore hair vitality and promote healthy growth.
Injectables
Minimally invasive injectables to smooth wrinkles and enhance facial contours.
Precision cosmetic surgery tailored to enhance and refine your natural beauty.
Body Surgery
Expertly performed body surgeries to reshape, contour, and enhance your physique.
Breast Surgery
Specialized breast surgeries to enhance shape, size, and symmetry for a natural look.
Cosmetic Andrology
Advanced procedures designed to enhance male aesthetics and address intimate concerns.
Cosmetic Gynaecology
Tailored surgical solutions to enhance feminine aesthetics and improve intimate well-being.
Facial Surgery
Precision facial surgeries to refine features and achieve natural, balanced results.
Fat Transfer/Removal
Advanced fat transfer and removal techniques to sculpt and enhance your body’s contours.
Comprehensive solutions to address a range of body concerns, from stubborn fat to skin laxity.
Breasts
Tailored solutions for breast concerns, including size, shape, and symmetry.
Other Areas
Targeted solutions for stubborn areas of the body, tailored to your unique needs.
Volume & Contouring
Specialized treatments to enhance body volume and improve overall contour for a balanced silhouette.
Holistic care focused on improving overall health and well-being for a balanced lifestyle.
Digestive Health
Comprehensive care to support digestive health and improve overall well-being.
Energy & Immunity
Holistic approaches to boost energy levels and strengthen your immune system for optimal health.
General Health
Personalized strategies to maintain and enhance your overall health and vitality.
Expert care for a wide variety of skin and facial concerns, promoting a healthy, glowing complexion.
Ageing Signs
Expert treatments to minimize ageing signs, rejuvenating your skin for a youthful glow.
Skin Texture & Tone
Advanced treatments to improve skin texture and even out tone for a smoother, radiant complexion.
Specific Areas
Targeted treatments to address skin concerns in specific facial areas for balanced, refined results.
Volume & Contouring
Tailored solutions to restore facial volume and enhance natural contours for a more youthful appearance.
When a friend uses your referral code, they'll get £50 off their first treatment, and you'll get £50 off your next one.
The more friends you invite, the more you earn.
★★★★★
20 Years of Safety: Trust in our 20 year track record and history of excellence
Award Winning Clinic: Over the last two decades we've received multiple awards
We do aesthetics better
While we are a skin clinic based in London, our impact is much greater. We focus on bringing excellent skin care to patients around the world.
Our experienced doctors are experts in cutting-edge dermatological procedures and skincare. You’re in luck when you choose us for skincare, because our team is here to meet all of your skincare demands.
Experience remarkable results with Polynucleotides. These treatments effectively diminish fine lines and wrinkles, leaving your complexion visibly smoother and more even.
Understanding Polynucleotides: The Key to Skin Regeneration
Polynucleotides, abbreviated as PN, is an innovative treatment from DNA traces turned into the most powerful dermatology procedure to have ever existed. This treatment stimulates collagen and elastin production and healing of post-inflammatory hyperpigmentation (redness) due to acne or sun damage. It also moisturizes your skin so that it looks plumper and radiant. Plus, these molecules reduce inflammation, irritation, redness, increase skin elasticity, and make you look younger. Giving your skin a dose of PN makes your skin look fresh and renewed.
Several effects of a Polynucleotide:
Polynucleotide treatments for the whole face generally take about 6 to 12 months before they wear off. Maintenance sessions may be necessary after this period to enhance the effectiveness of this therapy based on individual skin characteristics and goals. These sessions help maintain the rejuvenating effects of treatment leading to long standing improvement in the texture and appearance of your skin.
Polynucleotide treatments are excellent in promoting tissue healing, increasing collagen, and elastin production. Consequently, it leads to well-hydrated firmer skin that has reduced fine lines and wrinkles as well as a better surface texture. Polynucleotide is more than just filler; instead, it enables skin regeneration that leads to a prolonged natural glow. It is also a great anti-aging treatment.
By enhancing collagen production and rejuvenated skin, it helps tightens the skin, smooth out fine lines and wrinkles, and improve overall texture. Also great at hydrating the skin while minimizing sun damage or age spots appearance. Thus, providing a fresh and younger appearance on the neck & decolletage.
Your hair can benefit immensely from polynucleotides. This is because when administered around hair follicles they promote blood flow towards the scalp thereby nourishing hair from roots. This results in improved hair growth rate as well as thicker strands which have a healthy look overall. Whether you need stimulation for thinning hair or looking forward to vitality enhancement of your hair’s health, A polynucleotide treatment could make all the difference.
30 minutes - 1 hour
Not Required
None
Immediately
Immediately
Varies
24 Hours
24 Hours
Polynucleotides take a regenerative approach to skin health. They are naturally derived and support your cells by repairing and hydrating tissue. What I find particularly valuable is how they enhance the skin’s ability to restore itself over time. Unlike treatments that simply mask the signs of ageing, polynucleotides work to address the causes.
Dr Aamer Khan
MSC, CHD, MSBC
GMC: 3128431
It is preferable to begin with a consultation in which expectations regarding the procedure, necessary preparations, and actions to be taken prior to, during, and following the surgery are established.
We are now focused on all the preparations that must be taken. Making sure everything will go along to plan financially, emotionally, and physically before the procedure begins.
Polynucleotide treatments are excellent in promoting tissue healing, increasing collagen, and elastin production. Consequently, it leads to well-hydrated firmer skin that has reduced fine lines and wrinkles as well as a better surface texture. Polynucleotide is more than just filler.
The recovery time for polynucleotide injections is usually 1–2 days. However, recovery time can vary depending on the method used to administer the injections.
It is preferable to begin with a consultation in which expectations regarding the procedure, necessary preparations, and actions to be taken prior to, during, and following the surgery are established.
We are now focused on all the preparations that must be taken. Making sure everything will go along to plan financially, emotionally, and physically before the procedure begins.
Polynucleotide treatments are excellent in promoting tissue healing, increasing collagen, and elastin production. Consequently, it leads to well-hydrated firmer skin that has reduced fine lines and wrinkles as well as a better surface texture. Polynucleotide is more than just filler.
The recovery time for polynucleotide injections is usually 1–2 days. However, recovery time can vary depending on the method used to administer the injections.
Kamila Abduraimova
we had an issue but afterwards they called me and politely explained that it was a mistake and promised to train their staff for next time. and suggested a free treatment. I felt that everything was just misunderstanding. the doctor was very nice. Thank you for having me guys!
6th August 2025
Lee Hamill
This is the second visit to this clinic and can honestly say how friendly the staff are on arrival and both Doctors who have treated me were so knowledgeable and calm and mafe me feel at ease. Thoroughly recommend this clinic based on my two visit for cortisone injections.
14th July 2025
Y
Dr Omar was lovely, he explained everything clearly and didn’t make me feel rushed in making a decision. Great experience! Also the receptionist was lovely and welcoming
9th May 2025
Ashleigh Fitzgerald
I had a fantastic experience with Dr Omar and Dr Badat at Harley Street Skin Clinic. Very professional, friendly and helpful. I would highly recommend this clinic.
24th March 2025
Emily Dixon Slater
A great experience with the clinic. I booked a same day appointment and the very helpful reception staff went out of their way to accommodate me. Dr Omar was very kind and knowledgeable, taking the time to explain the treatment and providing lots of additional information and advice. Thank you!
18th March 2025
Polynucleotide treatments are possible through the use of either needles or tubes that are based on individual needs. Fine lines and wrinkles are targeted more precisely by needles compared to cannulas, which are good for larger areas and promote less bruising. A numbing cream should be expected to help soothe any stinging feeling. The procedure typically takes 15-30 minutes. Immediately after mild side effects like swelling or redness may follow. In order to heal totally, you need a treatment plan for sessions two or three weeks before big events. Minimizing downtime while enhancing the deep skin renewal is the ultimate goal here.
You may anticipate significant changes in aging symptoms such as wrinkles and fine lines after the treatment, also, it helps skin firmness leading to smoother skin texture. This treatment also results in an even skin tone, seeming and feeling moisturized while being velvety soft. With regular sessions, there is a marked transformation that rejuvenates the skin making it look youthful again.
Peptides act like healers and they help in aiding the skin tissues leading to the disappearance of acne scars over time. Use them more frequently and those marks will become less visible and your skin will look smoother and more even. The polynucleotide treatment also induces collagen that repairs sun damage and improves texture. Your face can look more attractive because of the skin health, these fixes can eliminate dark spots, wrinkles, etc.
Polynucleotides rescue sun damaged skin. It increases collagen production and rejuvenates the skin that results in gradual reduction of sunspots, finer lines on the face, and discolored pigmentation over time. With continued maintenance of polynucleotide treatment, it will bring back your youthful glow. Always make sure you don’t miss any of your treatments so that you get optimal outcomes.
Some clients might experience instant improvement such as increased moisture levels or a glowing effect. However, having smooth skin and reducing wrinkles is something that takes time. You will notice the full effects of the polynucleotide treatment after some sessions when your skin regeneration starts from within. Frequency of treatments will depend on your skin type and what you want to achieve with your skin. In most cases, one receives several treatments over several weeks or months to achieve desired outcomes. In most cases, you will need between three to six sessions depending on how much work your skin requires.
Polynucleotides possess versatility in treating different body parts. They can improve a person’s appearance within weeks from facial moisturizers that are also suitable for the neck and hands to those which rejuvenate any part of the body. Although facial rejuvenation is one common use for polynucleotides, they can also work wonders elsewhere on the body as well. It could even include sagging arms, legs, and thighs. In some instances, stretch marks and cellulite may appear less pronounced while skin might feel smoother and more toned after several sessions. That’s how you can rejuvenate your whole body through a Polynucleotide session.
With polynucleotide treatment involving injections, you may feel a tiny pinch or sting from the needle. This mild discomfort usually goes away quickly although certain parts of the body may experience more pain than others. Moreover, if you fear any form of pain before the procedure, you should consider using numbing cream on your skin to ensure no pain during the process. Applying polynucleotides topically is pretty straightforward. Creams or gels used for this purpose are mild so they do not cause any pain or discomfort as they are applied on the skin surface. Even better, some people find this activity to be relaxing. However, everyone’s skin is unique, individuals who experience itching or tenderness are always encouraged to report to medical practitioners involved, then treatment will continue as planned.
Caitlin Evans
Great experience as always and very efficient
6th August 2025
Edie Burgess
Lovely clinic, very attentive!
14th July 2025
Clare Ramsell
Very friendly staff and helpful doctor. Highly recommend.
23rd June 2025
Debra Rosenberg
Brilliant. Have been coming here for years!
20th June 2025
Alex Lipitch
Dr Omar treated me and was super. Thank you!
9th June 2025
The Olive Branch LDN
Wonderful first experience here- thanks so much Dr Stark!
16th May 2025
John
Very calming and professional
12th May 2025
Rhea Sahans
Excellent service by Dr Stark
14th May 2025
Anna Zhang
Very good
12th May 2025
Sinead McCann
Great experience with Dr Omar. Highly recommend
9th May 2025
Polynucleotide at Harley Street Skin Clinic administer this treatment with skill and expertise. Employing safe, long-established procedures and high-quality medical materials.
This is how how much our Polynucleotide costs:
Doctor:
Senior Doctor:
Lead Doctor:
Our prices represent the expertise of our GMC-registered doctors, the superior quality of the products we use and the convenience and comfort of our clinic. Elsewhere in the UK, in places such as Manchester, Newcastle or Leicester, the cost of treatments is less expensive, and treatments start from £250 per session upwards. But, there can also be less quality methods or end results with them. By choosing Harley Street SKin Clinic, you are choosing reputable care from individuals who care first and foremost about your safety and satisfaction.
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Stop your routine skin care for about one week before having your polynucleotide treatment. By suspending the use of topical products on your skin. This is a general rule; however, it is prudent to consult experts who can give advice that specifically caters to your skin’s necessities.
After the treatment of polynucleotides, one is recommended to avoid anything that might irritate your skin. These may include extreme sunlight exposure, excessive sweating during intense workouts as well as heavy cosmetics. Having gentle routines for skin care and taking note of what our skins need is a good way to ensure a smooth and successful recovery.
No specific dietary or lifestyle changes are needed, simply have a healthy living style which will help in prolonging the advantages that can be derived from polynucleotide treatment. This involves eating a balanced diet with lots of nutrients and minerals, ensuring that dehydration does not occur, limiting sun exposure, as well as using mild skincare products. It’s also important to know that skin treatments last longer if you are in good health generally.
Get that bounce back in your skin, as it becomes tighter and more elastic.
Say goodbye to sagging skin with a natural facelift.
Skin that is strong enough to fight off aging.
Post-treatment, you’ll notice an improvement in your skin quality - not just in texture and elasticity, but also in tone. Many patients tell me they look more rested and less tired within a week or two. It’s a subtle treatment, but one I find to be consistently effective.
Dr Mike Tee
BSC, MB, BCHIR, DLO, DRCOG, MRCGP
GMC: 3118018
Most activities can be resumed right after polynucleotide treatments. However, you should avoid heat exposure such as hot baths/showers and steam rooms for 48 hours after treatment. You may also want to wait 24 hours before resuming exercise routines. Your practitioner will give you complete instructions on what to do afterwards.
After getting polynucleotide treatment, people usually experience a 3-5 days swelling period before the body completely digests it. Avoid sun exposure and use mild cleansers.
While full results are usually seen around 5 weeks after the final session, many clients notice gradual improvements leading up to this point.
Polynucleotide injections are generally safe, but it’s necessary to consult with a qualified medical practitioner to assess the suitability. Pregnancy, breastfeeding, active skin infections, autoimmune disorders, bleeding disorders and allergies are examples of factors that may make individuals unsuitable for this treatment. Polynucleotides are made from fish and therefore they cannot be used by vegans. Although most people can tolerate its administration without problems because it suits any kind of skin including sensitive skins.
Polynucleotides usually have good tolerance, and the only adverse effects are injection site reactions like redness, swelling and bruising. The latter is not common. It is important to have proper consultation prior to treatment so that all possible risks can be evaluated for a particular patient. Such patients should be careful if they are allergic to seafood because despite the purification process which helps in reducing chances of DNA allergic reactions, they may still suffer from such conditions. Polynucleotide injections must not be given to pregnant or nursing women, as well as those planning to become pregnant soon.
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Need to reach us?
Contact or visit our clinic.
We're based in central London at the historic 14 Devonshire Pl which is only a short 2 minute walk from Regents Park tube station a 10 minute taxi journey to Kings Cross, and St Pancras stations.
We're open Monday - Friday 8am - 8pm, and Saturdays 9am - 5pm, feel free to drop in to talk to a member of our team where they can answer any of your questions.
Alternatively book an appointment, request a callback, or call us on 0207 4364441.
