Polynucleotides vs Profhilo: What is Right for Me?

Injectables have taken the beauty industry by storm in recent years when it comes to skin rejuvenation. But with so much to choose from, how are you to know what treatment option is right for you? Two of the most top-tier treatments available today are Polynucleotides and Profhilo, both of which can help hydrate, repair, and prevent the signs of aging in the skin. So, if you’re unsure if you want deep skin regeneration or a mega hydration boost, you came to the right place. This guide will help you sort out everything you should know so that you can choose what’s best for your skin.

What are Polynucleotides?

Imagine a highly effective skin treatment that has the ability to support the processes in your skin and repair it from within while derived from purified DNA fragments. These injectable molecules help repair, form, inflame, and deeply hydrate the skin down to the cellular level. Unlike traditional fillers, polynucleotides don’t only plump the skin, they actively heal and restore it from the inside.

How Polynucleotides work

Polynucleotides act on fibroblasts stimulating the collagen production. In other words, the skin gets firmer, healthier, and improves skin elasticity with each passing year. Also, they attract water molecules which contributes to better hydration and a plump, youthful skin.

What can Polynucleotides treat?

Fine lines and wrinkles
Acne scars
Dark circles under the eyes
Sun damage
Rosacea and skin redness
Overall skin hydration and elasticity

What is a Profhilo?

Profhilo is an injectable treatment with one of the highest concentrations of hyaluronic acid available on the market. Unlike dermal fillers, which target volume in specific areas, Profhilo disperses beneath the skin to deeply hydrate and tighten the whole face.

How Profhilo works

On each side of the face, five injection points are treated with Profhilo, Once injected, it disperses evenly, integrating into the skin to stimulate collagen and elastin production and deliver intense hydration. The result? Brighter, firmer, smoother skin.

What can Profhilo treat?

Improve skin texture
Fine lines and wrinkles
Loss of skin laxity
Dull, dehydrated skin
Mild sagging and volume loss
Collagen stimulation

What is the difference between Polynucleotides and Profhilo?

Polynucleotides:

Composition: Repairs the skin using DNA fragments.
Main benefit: Skin regeneration and healing.
Treatment areas: Face, neck, under-eyes, scars
Longevity: 6-12 months
Pain level: Minimal discomfort
Downtime: Little to none
Best for: Skin damage, redness, scars

Profhilo:

Composition: Uses pure hyaluronic acid.
Main benefit: Intense hydration and firming.
Treatment areas: Face, neck, décolletage
Longevity: 6 months
Pain level: Mild stinging
Downtime: 1-2 days of mild swelling
Best for: Hydration, lifting, anti-aging

Now let’s break it down further:

Composition

Polynucleotides are derived from purified DNA fragments and act as a natural stimulus for skin cells regeneration and healing. Profhilo, however, is ultra-pure hyaluronic acid intended to enhance hydration and elasticity.

Procedure and technique

Polynucleotides facilitate dermal healing and restoration. Profhilo treatment is carried out using the BAP (Bio Aesthetic Points) technique with 5 injection points on either side of the face for even spread.

Results, effectiveness and longevity

Polynucleotides: Results are gradual, with benefits lasting around 12 months.
Profhilo: Provides an instant skin booster of hydration, lasting about 6 months.

Pain and discomfort

There is slight discomfort involved with each treatment. Polynucleotides might cause a bit of stinging, and Profhilo can produce a mild burning sensation as it spreads under the skin.

Recovery and aftercare

Polynucleotides have virtually no downtime, and mild redness resolves quickly. Profhilo might cause swelling or slight bruising at injection sites for up to 48 hours.

Cost

Polynucleotides: £450 per session, £1,150 for three sessions, and £450 for top-up sessions.
Profhilo: £495 per session, £900 for the course of 2

Polynucleotides

Benefits:

Helps with deep skin repair and healing.
It helps to reduce redness, acne scars, and pigmentation.
Offers intense moisture and rejuvenation.

Drawbacks:

Results take time to develop.
Multiple sessions may be necessary.

Profhilo

Benefits:

Immediate hydration boost
Helps enhance skin quality, firmness, and elasticity to the skin.
Minimal downtime

Drawbacks

Shorter-lasting effects
Get hydration and lifting only

Before and after

The beauty of Polynucleotides and Profhilo is appreciated when we observe the change in our skin. Individual outcomes will vary from one person to next but many patients experience a distinct increase in skin hydration, firmness and general skin health.

Polynucleotides Before and After

Patients who undergo Polynucleotide treatments often see:

Decreased redness and inflammation
Smoother skin texture with lesser acne marks
Tight, bouncy skin with a youthful radiance

Profhilo Before and After

After Profhilo treatments, most patients experience:

A visible plumping and hydration boost that gives the skin a more dewy, plump appearance.
Firmness and elasticity of the skin improved and fine lines decreased.
A natural, refreshed look without too much volume

To see results in real patients, schedule a consultation to see before and after images and discuss how these treatments can be a win for your skin.

Desired skin goals

Need to fix and nurture damaged skin? Polynucleotides might be the way to go.
In need of the sort of hydration that gives you instant glow? Profhilo could be ideal.

Skin type

Polynucleotides are for sensitive, acne-prone or inflamed skin.
Profhilo is ideal for dry, dehydrated or aging skin.

Frequency of treatments

Profhilo works best with two initial sessions a month apart and maintenance every six months.
Polynucleotides usually require an initial treatment of three to four sessions and maintenance once every 9-12 months.

Lifestyle and budget factors

Profhilo leaves faster results and requires fewer sessions, making it an ideal solution for busy people.
Polynucleotides provide more profound skin healing, but need a greater upfront time commitment.

Glow, Hydrate, Rejuvenate – Your Best Skin Starts Here!

Need help deciding what treatment is best for you? At Harley Street Skin Clinic our expert practitioners will be happy to evaluate your skin’s specific needs and tailor a treatment plan accordingly.

FAQs

Which is better, polynucleotide or Profhilo?

That depends on what your skin is trying to achieve. Polynucleotides are great for repairing skin deep down, Profhilo is incredible for hydration and firmness in the skin at a higher level.